Research Down Syndrome´s Mission

Research Down Syndrome (RDS) is a non-profit foundation that supports Down syndrome cognitive research, an area that in the last 5 years has experienced great advances towards developing biomedical therapies to treat the cognitive impairment of people of all ages with Down syndrome. The potential of these treatments to address Down syndrome cognitive dysfunction is tremendous - improving memory, learning and communication – and expanding and enhancing life opportunities for these individuals.

Until recently, the medical and research community considered the cognitive impairment associated with Down syndrome to be too complex to understand, offering no hope for the development of treatments. Now scientists have identified unique biological mechanisms associated with cognitive dysfunction in Down syndrome, suggesting the promise of targeted biomedical therapies that could lead to improvement in the intellectual difficulties experienced by those with Down syndrome.

In recent decades, improved health care, expanded educational and community opportunities, and the support of families and advocacy groups has improved the quality of life for individuals with Down syndrome. As a result, the life expectancy of those with Down syndrome has more than doubled -- underscoring the importance of development of treatments that will assist this population to achieve and maintain independent living. We believe that individuals with Down syndrome should have access to effective drug therapies in a manner consistent with many medical conditions.

Research Down Syndrome(a 501(c)(3) approved foundation) will support world-class scientists with the goal of continuing these revolutionary advances. RDS, through the support of friends, has already raised hundreds of thousands of dollars to support the RDS Foundation and Down syndrome cognitive research. This support and low foundation administrative costs ensure that a greater proportion of your contributions go directly to research.

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Latest News

8
May

A Night of Art and Blues: RDS Fundraiser in South Bend, IN

Here is an impressive video produced by the event coordinators of A Night of Art and Blues, a fundraiser for Research Down Syndrome being held in South Bend, IN on May 11. Parents and others speak about the remarkable revolution underway in research to understand and treat learning disabilities in Down syndrome. Join the Revolution by donating to the event

1
May

RDS Co-Sponsors Down Syndrome/Alzheimer’s Disease Workshop

 

RDS was a co-sponsor of Advancing Treatments for Alzheimer’s Disease in Individuals with Down Syndrome, held April 15-16, near Washington, D.C. Twelve presentations with follow up panel discussions were grouped in the following areas:
1. Disease Mechanisms
2. Model Systems for Studying Connections between AD and Ds
3. Cognitive Outcomes Measures
4. Biomarkers
5. Developing Therapeutics
For each of the sections, attendees discussed 1) Current strengths and weaknesses in areas of

16
Apr

Down Syndrome Cognition Workshop in Washington

 

A three day Workshop, Cognition in Down Syndrome: Molecular, Cellular and Behavioral Features and the Promise of Pharmacotherapies, was held in Washington on April 13-15. Research Down Syndrome was a co-sponsor of this research meeting. Presentations and posters addressed:
Chromosome 21 genes and processes they influence
Lessons from other causes of Intellectual Disabilities(ID)
Mechanisms of ID in DS
Pharmacology in Model Systems
DS Cognitive and Neurological Features, including sleep

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Roche Clinical Trials
Clinical Trials Locations & Contacts

 

Research Down Syndrome Running Events Upcoming Races RDS Runners Blog Montclair, NJ 5K

 

 

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